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Cadherin 5 (CDH5) Antibody
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Catalogue No: abx031662
Price:
US$326.25
(Size: 80 µl)
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CDH5 is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.
Research Articles on Cadherin 5 (CDH5)
| Target | Cadherin 5 (CDH5) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, FCM: 1/25. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 106-134 amino acids from the N-terminal region of human VE Cadherin. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P33151 (UniProt, ExPASy) |
| UniProt Secondary AC | Q4VAI5, Q4VAI6 |
| UniProt Entry Name | CADH5_HUMAN |
| KEGG | hsa:1003 |
| String | 9606.ENSP00000344115 |
| Molecular Weight | Calculated MW: 87.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |