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Vascular Endothelial Growth Factor Receptor 2 / VEGFR2 (KDR) Antibody
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Catalogue No: abx004288
Price:
US$203.00
(Size: 20 µl)
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Vascular Endothelial Growth Factor Receptor 2 / VEGFR2 (KDR) Antibody is a Rabbit Polyclonal antibody against Vascular Endothelial Growth Factor Receptor 2 / VEGFR2 (KDR). Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of this gene are implicated in infantile capillary hemangiomas.
Research Articles on Vascular Endothelial Growth Factor Receptor 2 / VEGFR2 (KDR)
| Target | Vascular Endothelial Growth Factor Receptor 2 / VEGFR2 (KDR) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1150-1250 of human VEGF Receptor 2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P35968 (UniProt, ExPASy) |
| UniProt Secondary AC | A2RRS0, B5A925, C5IFA0, O60723, Q14178 |
| UniProt Entry Name | VGFR2_HUMAN |
| Gene Symbol | KDR |
| GeneID | 3791 |
| NCBI Accession | NP_002244.1 |
| KEGG | hsa:3791 |
| String | 9606.ENSP00000263923 |
| Enzyme Commission Number | EC 2.7.10.1 EC 2.7.10 |
| Molecular Weight | Calculated MW: 152 kDa Observed MW: 210/230 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |