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Vinculin (VCL) Antibody
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Catalogue No: abx239877
Price:
US$406.00
(Size: 100 µg)
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Vinculin (VCL) Antibody is a Mouse Monoclonal antibody for the detection of Vinculin. Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin) -binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion. Vinculin is a 117-kDa, 1, 066-amino-acid protein which is ubiquitously expressed. Its splice variant, metavinculin (124 kDa), is muscle-specific.
Research Articles on Vinculin (VCL)
| Target | Vinculin (VCL) |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | WB: 1/2000 - 1/20000, IHC: 1/50 - 1/500, IF/ICC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | vinculin |
| Isotype | IgG1 |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P18206 (UniProt, ExPASy) |
| UniProt Secondary AC | Q16450, Q5SWX2, Q7Z3B8, Q8IXU7 |
| Gene Symbol | VCL |
| GeneID | 7414 |
| OMIM | 193065 |
| HGNC | 12665 |
| Ensembl | ENSG00000035403 |
| Molecular Weight | Observed MW: 124 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |