X-Ray Repair Cross Complementing 1 (XRCC1) Antibody

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Catalogue No: abx032554
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Target X-Ray Repair Cross Complementing 1 (XRCC1)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, IF/ICC, FCM
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/25, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 407-435 amino acids from the Central region of human XRCC1.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P18887 (UniProt, ExPASy)
UniProt Secondary AC Q6IBS4, Q9HCB1
UniProt Entry Name XRCC1_HUMAN
Gene Symbol XRCC1
KEGG hsa:7515
String 9606.ENSP00000262887
Molecular Weight Calculated MW: 69.5 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on X-Ray Repair Cross Complementing 1 (XRCC1)
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