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X-Ray Repair Cross Complementing 1 (XRCC1) Antibody
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Catalogue No: abx000721
Price:
US$348.00
(Size: 60 µl)
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XRCC1 Antibody is a Rabbit Polyclonal antibody against XRCC1. The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Research Articles on X-Ray Repair Cross Complementing 1 (XRCC1)
| Target | X-Ray Repair Cross Complementing 1 (XRCC1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human XRCC1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P18887 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6IBS4, Q9HCB1 |
| UniProt Entry Name | XRCC1_HUMAN |
| Gene Symbol | XRCC1 |
| GeneID | 7515 |
| NCBI Accession | NP_006288.2 |
| KEGG | hsa:7515 |
| String | 9606.ENSP00000262887 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
