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X-Ray Repair Cross Complementing 3 (XRCC3) Antibody
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Catalogue No: abx001746
Price:
US$217.50
(Size: 20 µl)
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XRCC3 Antibody is a Rabbit Polyclonal antibody against XRCC3. This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].
Research Articles on X-Ray Repair Cross Complementing 3 (XRCC3)
| Target | X-Ray Repair Cross Complementing 3 (XRCC3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 62-346 of human XRCC3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O43542 (UniProt, ExPASy) |
| UniProt Secondary AC | O43568, Q9BU18 |
| UniProt Entry Name | XRCC3_HUMAN |
| Gene Symbol | XRCC3 |
| GeneID | 7517 |
| NCBI Accession | NP_001093588.1 |
| KEGG | hsa:7517 |
| String | 9606.ENSP00000451974 |
| Molecular Weight | Calculated MW: 38 kDa Observed MW: 37 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |