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X-Ray Repair Cross-Complementing Protein 4 (XRCC4) Antibody
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Catalogue No: abx030630
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V (D) J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq].
Research Articles on X-Ray Repair Cross-Complementing Protein 4 (XRCC4)
| Target | X-Ray Repair Cross-Complementing Protein 4 (XRCC4) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 205-234 amino acids from the Central region of human XRCC4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13426 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K3X4, Q9BS72, Q9UP94 |
| UniProt Entry Name | XRCC4_HUMAN |
| KEGG | hsa:7518 |
| String | 9606.ENSP00000421491 |
| Molecular Weight | Calculated MW: 38.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |