X-Ray Repair Cross-Complementing Protein 4 (XRCC4) Antibody

XRCC4 Antibody is a Rabbit Polyclonal antibody against XRCC4. The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq, Sep 2008].

Target	X-Ray Repair Cross-Complementing Protein 4 (XRCC4)
Clonality	Polyclonal
Reactivity	Human, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-336 of human XRCC4.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13426 (UniProt, ExPASy)
UniProt Secondary AC	A8K3X4, Q9BS72, Q9UP94
UniProt Entry Name	XRCC4_HUMAN
Gene Symbol	XRCC4
GeneID	7518
NCBI Accession	NP_001304941.1
KEGG	hsa:7518
String	9606.ENSP00000421491
Molecular Weight	Calculated MW: 38 kDa Observed MW: 55 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on X-Ray Repair Cross-Complementing Protein 4 (XRCC4)

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