X-Ray Repair Cross Complementing 5 (XRCC5) Antibody

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Catalogue No: abx004499
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
XRCC5 Antibody is a Rabbit Polyclonal antibody against XRCC5. The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Target X-Ray Repair Cross Complementing 5 (XRCC5)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC, IP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, IHC-P: 1/100 - 1/200, IF/ICC: 1/20 - 1/100, IP: 0.5-4 µg/200-400 µg whole cell extracts. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 543-732 of human Ku80.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P13010 (UniProt, ExPASy)
UniProt Secondary AC A8K3X5, Q0Z7V0, Q4VBQ5, Q53HH7, Q7M4N0, Q9UCQ0, Q9UCQ1
UniProt Entry Name XRCC5_HUMAN
Gene Symbol XRCC5
GeneID 7520
NCBI Accession NP_066964.1
KEGG hsa:7520
String 9606.ENSP00000375978
Molecular Weight Calculated MW: 83 kDa
Observed MW: 86 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on X-Ray Repair Cross Complementing 5 (XRCC5)


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