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Tyrosine-tRNA Ligase, Cytoplasmic (YARS1) Antibody
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Catalogue No: abx005209
Price:
US$203.00
(Size: 20 µl)
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YARS1 Antibody is a Rabbit Polyclonal antibody against YARS1. Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.
Research Articles on Tyrosine-tRNA Ligase, Cytoplasmic (YARS1)
| Target | Tyrosine-tRNA Ligase, Cytoplasmic (YARS1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IP: 0.5-4 µg/200-400 µg whole cell extracts. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human YARS. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P54577 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KWK4, D3DPQ4, O43276, Q53EN1 |
| UniProt Entry Name | SYYC_HUMAN |
| Gene Symbol | YARS1 |
| GeneID | 8565 |
| OMIM | 603623 |
| NCBI Accession | NP_003671.1 |
| HGNC | 12840 |
| KEGG | hsa:8565 |
| String | 9606.ENSP00000362576 |
| Molecular Weight | Calculated MW: 59 kDa Observed MW: 59 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |