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Nuclease-Sensitive Element-Binding Protein 1 (YBX1) Antibody
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Catalogue No: abx032789
Price:
US$326.25
(Size: 80 µl)
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YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. This protein binds and stabilizes cytoplasmic mRNA and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. It regulates the transcription of numerous genes and promotes separation of DNA strands that contain mismatches or are modified by cisplatin. It has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), and it may play a role in DNA repair.
Research Articles on Nuclease-Sensitive Element-Binding Protein 1 (YBX1)
| Target | Nuclease-Sensitive Element-Binding Protein 1 (YBX1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IF/ICC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 276-305 amino acids from the C-terminal region of human YBX1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P67809 (UniProt, ExPASy) |
| UniProt Secondary AC | P16990, P16991, Q14972, Q15325, Q5FVF0 |
| UniProt Entry Name | YBOX1_HUMAN |
| KEGG | hsa:4904 |
| String | 9606.ENSP00000361626 |
| Molecular Weight | Calculated MW: 35.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow and Xenopus YBX1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |