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Nuclease-Sensitive Element-Binding Protein 1 (YBX1) Antibody
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Catalogue No: abx031312
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
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Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. Regulates the transcription of numerous genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability.
Research Articles on Nuclease-Sensitive Element-Binding Protein 1 (YBX1)
| Target | Nuclease-Sensitive Element-Binding Protein 1 (YBX1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IF/ICC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 149-178 amino acids from the Central region of human YBX1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P67809 (UniProt, ExPASy) |
| UniProt Secondary AC | P16990, P16991, Q14972, Q15325, Q5FVF0 |
| UniProt Entry Name | YBOX1_HUMAN |
| NCBI Accession | NP_004550.2 |
| KEGG | hsa:4904 |
| String | 9606.ENSP00000361626 |
| Molecular Weight | Calculated MW: 35.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow and Rabbit YBX1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |