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YTH Domain-Containing Family Protein 2 (YTHD2) Antibody
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Catalogue No: abx028773
Price:
US$326.25
(Size: 80 µl)
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YTHDF2 is a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosme 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene.
Research Articles on YTH Domain-Containing Family Protein 2 (YTHD2)
| Target | YTH Domain-Containing Family Protein 2 (YTHD2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 551-579 amino acids from the C-terminal region of human YTHD2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Y5A9 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NKG4, A8K966, B4E1G7, D3DPM8, Q5VSZ9, Q8TDH0, Q9BUJ5 |
| UniProt Entry Name | YTHD2_HUMAN |
| Gene Symbol | YTHDF2 |
| String | 9606.ENSP00000362918 |
| Molecular Weight | Calculated MW: 62.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Cow and Monkey YTHDF2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |