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Zika Virus Envelope (ZIKV E) Antibody
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Catalogue No: abx201401
Price:
US$362.50
(Size: 50 µl)
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Zika Virus Envelope (ZIKV E) Antibody (Strain Zika SPH2015) is a Mouse Monoclonal for the detection of Zika Virus Envelope (ZIKV E). The Envelope of Zika virus is resposible for receptor binding and membrane. Analysis of the envelope protein of Zika, from Brazilian Zika SPH215 (KU321639), indicates predicted B and T cell epitopes in peptides that are consistent to those reported for dengue, YFYF and Japanese encephalitis. The envelope Domain II B cell epitope, to which much dengue non-neutralizing cross reaction is attributed, is also conserved also in Zika virus, consistent with prior field observations of cross reactivity with dengue and YF. Domain III of the Zika envelope protein, likely the main specific neutralizing domain, is distinct from recent Brazilian dengue isolates and a recent Peruvian YF isolate (GQ379163), 76% of possible major histocompatibility complex class (MHC) I and MHC II binding peptides and potential B cell linear epitopes are unique to Zika virus.
Research Articles on Zika Virus Envelope (ZIKV E)
| Target | Zika Virus Envelope (ZIKV E) |
| Clonality | Monoclonal |
| Reactivity | Virus |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/1000 - 1/2000, WB: 1/1000 - 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant ZIKV (strain Zika SPH2015) Envelope protein (Domain III) |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified by Protein A affinity chromatography. 0.2 µm filtered. |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Buffer | PBS. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
| Directions for use | Centrifuge before opening to ensure complete recovery of vial contents. |