Aminomethyltransferase, Mitochondrial (AMT) Antibody

The enzyme system for cleavage of glycine (glycine cleavage system; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase; MIM 238300), H protein (a lipoic acid-containing protein; MIM 238330), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase; MIM 238331). Glycine encephalopathy (GCE; MIM 605899) may be due to a defect in any one of these enzymes.

Target	Aminomethyltransferase, Mitochondrial (AMT)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human AMT.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P48728 (UniProt, ExPASy)
UniProt Secondary AC	A8K3I5, B4DE61, B4DJQ0, E9PBG1, Q96IG6
UniProt Entry Name	GCST_HUMAN
KEGG	hsa:275
String	9606.ENSP00000273588
Molecular Weight	Calculated MW: 43.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse AMT.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Aminomethyltransferase, Mitochondrial (AMT)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue