Angiopoietin-1 (ANGPT1) Antibody

Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.

Target	Angiopoietin-1 (ANGPT1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 374-402 amino acids from the C-terminal region of human ANGPT1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15389 (UniProt, ExPASy)
UniProt Secondary AC	Q5HYA0
UniProt Entry Name	ANGP1_HUMAN
KEGG	hsa:284
String	9606.ENSP00000428340
Molecular Weight	Calculated MW: 57.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow and Pig ANGPT1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Angiopoietin-1 (ANGPT1)

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