Centromere Protein S (APITD1) Antibody

APITD1 was identified in the neuroblastoma tumour suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF (II) 31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumours, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway.

Target	Centromere Protein S (APITD1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 48-74 amino acids from the Central region of human APITD1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q8N2Z9 (UniProt, ExPASy)
UniProt Secondary AC	Q8NFE5, Q8NFG5
UniProt Entry Name	CENPS_HUMAN
Gene Symbol	CENPS
KEGG	hsa:100526739 hsa:378708
String	9606.ENSP00000308583
Molecular Weight	Calculated MW: 15.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow CENPS.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Centromere Protein S (APITD1)

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