Bone Morphogenetic Protein 7 (Bmp7) Antibody

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.

Target	Bone Morphogenetic Protein 7 (Bmp7)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human Bmp7.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P18075 (UniProt, ExPASy)
UniProt Secondary AC	Q9H512, Q9NTQ7
UniProt Entry Name	BMP7_HUMAN
KEGG	hsa:655
String	9606.ENSP00000379204
Molecular Weight	Calculated MW: 49.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse BMP7.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Bone Morphogenetic Protein 7 (Bmp7)

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