Chromobox Protein Homolog 1 (CBX1) Antibody

CBX1 Antibody is a Rabbit Polyclonal antibody against CBX1. This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Target	Chromobox Protein Homolog 1 (CBX1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HP1 beta/CBX1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P83916 (UniProt, ExPASy)
UniProt Secondary AC	P23197
UniProt Entry Name	CBX1_HUMAN
Gene Symbol	CBX1
GeneID	10951
NCBI Accession	NP_006798.1
KEGG	hsa:10951
String	9606.ENSP00000377060
Molecular Weight	Calculated MW: 21 kDa Observed MW: 21 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Chromobox Protein Homolog 1 (CBX1)

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