Cell Division Cycle 25A (Cdc25A) Antibody

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.

Target	Cell Division Cycle 25A (Cdc25A)
Clonality	Polyclonal
Reactivity	Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide selected from the N-terminal region of human Cdc25A.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P30304 (UniProt, ExPASy)
UniProt Secondary AC	Q8IZH5, Q96IL3, Q9H2F2
UniProt Entry Name	MPIP1_HUMAN
KEGG	hsa:993
String	9606.ENSP00000303706
Molecular Weight	Calculated MW: 59.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cell Division Cycle 25A (Cdc25A)

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