Cell Division Cycle Protein 7 (CDC7) Antibody

CDC7L1 is predominantly localized in the nucleus and is a cell division cycle protein with kinase activity. Although expression levels of the protein appear to be constant throughout the cell cycle, the protein kinase activity appears to increase during S phase. It has been suggested that the protein is essential for initiation of DNA replication and that it plays a role in regulating cell cycle progression. Overexpression of this gene product may be associated with neoplastic transformation for some tumors.

Target	Cell Division Cycle Protein 7 (CDC7)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CDC7 (CDC7L1).
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O00311 (UniProt, ExPASy)
UniProt Secondary AC	D3DT31, O00558, Q5T5U5
UniProt Entry Name	CDC7_HUMAN
Gene Symbol	CDC7
NCBI Accession	NP_001127891.1 NP_001127892.1 NP_003494.1
KEGG	hsa:8317
String	9606.ENSP00000393139
Molecular Weight	Calculated MW: 63.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cell Division Cycle Protein 7 (CDC7)

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