Claudin-22 (CLDN22) Antibody

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3' UTR of the WWC2 gene (GeneID: 80014) on the opposite strand.

Target	Claudin-22 (CLDN22)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 90-117 amino acids from the Central region of human CLDN22.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q8N7P3 (UniProt, ExPASy)
UniProt Entry Name	CLD22_HUMAN
Gene Symbol	CLDN22
KEGG	hsa:53842
String	9606.ENSP00000318113
Molecular Weight	Calculated MW: 24.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Claudin-22 (CLDN22)

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