Doublecortin-Like And CAM Kinase-Like 1 (DCAMKL1) Antibody

Doublecortin-like kinase (DCAMKL1) (Ser/Thr protein kinase family) is essential for proper neurogenesis, neuronal migration, and axonal wiring. DCAMKL1 is involved in a calcium-signaling pathway controling neuronal migration in the developing brain, and participates in functions of the mature nervous system. DCAMKL1 protein shares high homology with doublecortin (DCX). DCLK, but not DCX, is highly expressed in regions of active neurogenesis in the neocortex and cerebellum. DCAMKL1 controls mitotic division by regulating spindle formation and also determines the fate of neural progenitors during cortical neurogenesis.

Target	Doublecortin-Like And CAM Kinase-Like 1 (DCAMKL1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/8000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 690-720 amino acids from the C-terminal region of human DCAMKL1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O15075 (UniProt, ExPASy)
UniProt Secondary AC	B7Z3E9, Q5VZY8, Q5VZZ0, Q5VZZ1
Gene Symbol	DCAMKL1
NCBI Accession	NP_001182344.1 NP_001182345.1 NP_004725.1
Molecular Weight	Calculated MW: 82.2 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Doublecortin-Like And CAM Kinase-Like 1 (DCAMKL1)

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