EPH Receptor A4 (EphB4) Antibody

EphB4: EPH receptor B4.Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system.Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins.The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.

Target	EPH Receptor A4 (EphB4)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA
Host	Mouse
Recommended dilutions	ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of EphB4 (aa562-612)expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P54760 (UniProt, ExPASy)
UniProt Secondary AC	B5A970, B5A971, B5A972, Q7Z635, Q9BTA5, Q9BXP0
UniProt Entry Name	EPHB4_HUMAN
Gene Symbol	EPHB4
GeneID	2050
OMIM	600011
HGNC	3395
KEGG	hsa:2050
Ensembl	ENSG00000196411
String	9606.ENSP00000350896
Molecular Weight	108 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on EPH Receptor A4 (EphB4)

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