FK-506, also known as Fujimycin or Tacrolimus, is a small molecule which can act as a FKBP inhibitor. It is provided as a white powder.
It is a macrolide that prevents the dephosphorylation of NF-AT, and reduces peptidyl-prolyl isomerase activity by binding to FKBP12, creating a new complex that interacts with and inhibits calcineurin.
This product acts on the following target types: Immunophilin, Phosphatase, Antibiotic.
This product acts on the following biochemical pathways: Proliferation, Cell cycle, Mtor.
This product may be of interest in the following research areas and diseases: Immunology, Infectious disease.
This product may act as a Coronavirus inhibitor: mTORC1 pathway members interact with SARS-CoV-2 N and Orf8 proteins.
Please note that our chemical products are for scientific research use only and are not for medical or veterinary use. This product can only be dispatched to a scientific business or laboratory address.
Target |
FK-506 |
Form |
Solid |
Reconstitution |
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 50 mg/ml). |
Storage |
Store desiccated at -20 °C. |
Molecular Weight |
804.04 g/mol |
Buffer |
Not applicable. |
CAS Number |
104987-11-3 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Research Articles on FK-506