FK506 Binding Protein 1A (FKBP1A) Antibody

FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.

Target	FK506 Binding Protein 1A (FKBP1A)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 55-83 amino acids from the C-terminal region of human FKBP1A.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P62942 (UniProt, ExPASy)
UniProt Secondary AC	D3DVW6, P20071, Q4VC47, Q6FGD9, Q6LEU3, Q9H103, Q9H566
UniProt Entry Name	FKB1A_HUMAN
KEGG	hsa:2280
String	9606.ENSP00000383003
Molecular Weight	Calculated MW: 12 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow and Rabbit FKBP1A.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on FK506 Binding Protein 1A (FKBP1A)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue