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Proto-Oncogene C-Fos (FOS) Antibody
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Catalogue No: abx011653
Price:
US$420.50
(Size: 100 µl)
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The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Research Articles on Proto-Oncogene C-Fos (FOS)
| Target | Proto-Oncogene C-Fos (FOS) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human FOS expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P01100 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K4E2, B4DQ65, P18849 |
| UniProt Entry Name | FOS_HUMAN |
| Gene Symbol | FOS |
| GeneID | 2353 |
| OMIM | 164810 |
| HGNC | 3796 |
| KEGG | hsa:2353 |
| Ensembl | ENSG00000170345 |
| String | 9606.ENSP00000306245 |
| Molecular Weight | 40.7 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |