Ferritin Heavy Chain (FTH1) Antibody

FTH1 Antibody is a Rabbit Polyclonal antibody against FTH1. This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.

Target	Ferritin Heavy Chain (FTH1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-183 of human Ferritin Heavy Chain.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P02794 (UniProt, ExPASy)
UniProt Secondary AC	B3KNR5, Q3KRA8, Q3SWW1
UniProt Entry Name	FRIH_HUMAN
Gene Symbol	FTH1
GeneID	2495
NCBI Accession	NP_002023.2
KEGG	hsa:2495
String	9606.ENSP00000273550
Molecular Weight	Calculated MW: 21 kDa Observed MW: 21 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ferritin Heavy Chain (FTH1)

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