Galactosylceramidase (GALC) Antibody

Galactosylceramidase (GALC) Antibody is a Rabbit Polyclonal antibody for the detection of Galc.

This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Target	Galactosylceramidase (GALC)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	galactosylceramidase
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P54803 (UniProt, ExPASy)
UniProt Secondary AC	B4DKE8, B4DYN1, B4DZJ8, B7Z7Z2, J3KN25, J3KPP8, Q8J030
UniProt Entry Name	GALC_HUMAN
Gene Symbol	GALC
GeneID	2581
KEGG	hsa:2581
String	9606.ENSP00000261304
Molecular Weight	Observed MW: 80 kDa, 50 kDa, 30 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Galactosylceramidase (GALC)

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