Growth Factor, Augmenter of Liver Regeneration (GFER) Antibody

The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene.

Target	Growth Factor, Augmenter of Liver Regeneration (GFER)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 67-94 amino acids from the Central region of human GFER.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P55789 (UniProt, ExPASy)
UniProt Secondary AC	Q53YM6, Q8TAH6, Q9H290, Q9UK40
UniProt Entry Name	ALR_HUMAN
NCBI Accession	NP_005253.3
KEGG	hsa:2671
String	9606.ENSP00000248114
Molecular Weight	Calculated MW: 23.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Growth Factor, Augmenter of Liver Regeneration (GFER)

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