Guanine Monophosphate Synthase (GMPS) Antibody

GMPS Antibody is a Rabbit Polyclonal antibody against GMPS. In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.

Target	Guanine Monophosphate Synthase (GMPS)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IP: 0.5-4 µg/200-400 µg whole cell extracts. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 394-693 of human GMPS.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P49915 (UniProt, ExPASy)
UniProt Secondary AC	A8K639, B4DXV7, F8W720
UniProt Entry Name	GUAA_HUMAN
Gene Symbol	GMPS
GeneID	8833
NCBI Accession	NP_003866.1
KEGG	hsa:8833
String	9606.ENSP00000419851
Molecular Weight	Calculated MW: 77 kDa Observed MW: 80 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Guanine Monophosphate Synthase (GMPS)

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