Guanine Nucleotide Exchange Factor VAV3 (VAV3) Antibody

Guanine Nucleotide Exchange Factor VAV3 (VAV3) Antibody is a Rabbit Polyclonal antibody for the detection of VAV3.

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Target	Guanine Nucleotide Exchange Factor VAV3 (VAV3)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Guanine nucleotide exchange factor VAV3
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q9UKW4 (UniProt, ExPASy)
UniProt Entry Name	VAV3_HUMAN
Gene Symbol	VAV3
GeneID	10451
OMIM	605541
HGNC	12659
Ensembl	ENSG00000134215
String	9606.ENSP00000359073
Molecular Weight	Observed MW: 90-100 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Guanine Nucleotide Exchange Factor VAV3 (VAV3)

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