Hepatocyte Nuclear Factor 4 Alpha (HNF4A) Antibody

HNF4A is a nuclear transcription factor which binds DNA as a homodimer. This protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This protein may play a role in development of the liver, kidney, and intestines. Mutations in HNF4A gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I.

Target	Hepatocyte Nuclear Factor 4 Alpha (HNF4A)
Clonality	Polyclonal
Reactivity	Human, Rat
Tested Applications	ELISA, WB, IHC, IF/ICC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 281-312 amino acids from the Central region of human HNF4A.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P41235 (UniProt, ExPASy)
UniProt Entry Name	HNF4A_HUMAN
NCBI Accession	NP_000448.3 NP_001025174.1 NP_001025175.1 NP_001245284.1 NP_787110.2 NP_849181.1
KEGG	hsa:3172
String	9606.ENSP00000312987
Molecular Weight	Calculated MW: 52.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse HNF4A.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Hepatocyte Nuclear Factor 4 Alpha (HNF4A)

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