Kremen Protein 2 (KREMEN2) Antibody

This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT) /beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

Target	Kremen Protein 2 (KREMEN2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 248-276 amino acids from the Central region of human KREMEN2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q8NCW0 (UniProt, ExPASy)
UniProt Secondary AC	B4DXF6, I3L2S2, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9
UniProt Entry Name	KREM2_HUMAN
Gene Symbol	KREMEN2
KEGG	hsa:79412
String	9606.ENSP00000304422
Molecular Weight	Calculated MW: 48.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Kremen Protein 2 (KREMEN2)

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