Megakaryocyte Associated Tyrosine Kinase (MATK) Antibody

MATK has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.

Target	Megakaryocyte Associated Tyrosine Kinase (MATK)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MATK.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P42679 (UniProt, ExPASy)
UniProt Secondary AC	B3KNZ9, Q9NST8
UniProt Entry Name	MATK_HUMAN
Gene Symbol	MATK
KEGG	hsa:4145
String	9606.ENSP00000378485
Molecular Weight	Calculated MW: 56.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Megakaryocyte Associated Tyrosine Kinase (MATK)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue