Myelin Basic Protein (MBP) Antibody
REQUEST MORE INFO
Price:
US$326.25
(Size: 80 µl)
Click on the image to see the image legend
MBP is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called Golli-MBP) that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.
Target |
Myelin Basic Protein (MBP) |
Clonality |
Polyclonal |
Reactivity |
Human |
Tested Applications |
ELISA, WB |
Host |
Rabbit |
Recommended dilutions |
WB: 1/16000. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation |
Unconjugated |
Immunogen |
KLH-conjugated synthetic peptide between 177-209 amino acids from human MBP. |
Isotype |
IgG |
Form |
Liquid |
Purification |
Purified through a protein A column, followed by peptide affinity purification. |
Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
UniProt Primary AC |
P02686 (UniProt,
ExPASy)
|
UniProt Entry Name |
MBP_HUMAN |
Gene Symbol |
MBP |
KEGG |
hsa:4155
|
String |
9606.ENSP00000380958
|
Molecular Weight |
Calculated MW: 33.1 kDa |
Buffer |
PBS containing 0.09% sodium azide. |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |
Research Articles on Myelin Basic Protein (MBP)