Midline 1 (MID1) Antibody

MID1 Antibody is a Rabbit Polyclonal antibody against MID1. The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Multiple different transcript variants are generated by alternate splicing; however, the full-length nature of some of the variants has not been determined.

Target	Midline 1 (MID1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 478-667 of human MID1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O15344 (UniProt, ExPASy)
UniProt Secondary AC	B2RCG2, O75361, Q9BZX5
UniProt Entry Name	TRI18_HUMAN
Gene Symbol	MID1
GeneID	4281
NCBI Accession	NP_000372.1
KEGG	hsa:4281
String	9606.ENSP00000312678
Molecular Weight	Calculated MW: 75 kDa Observed MW: 75 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	0.54 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Midline 1 (MID1)

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