Proto-Oncogene Serine/threonine-Protein Kinase Mos (Mos) Antibody

MOS is a proto oncogene (c-Mos) encoded protein serine/threonine kinase. MOS is a monomeric protein that indirectly activates MAP kinase (Erk1/2) by directly phosphorylating MAP kinase kinase (Mck, MAPKK, MKK). MOS is known as a cytostatic factor (CSF) and is also thought to arrest unfertilized amphibian and mammalian cells during M phase, thus regulating oocyte maturation. MOS is destroyed before fertilisation, after exit from meiosis II, making it a good marker for studies of eggs during oogenesis and maturation.

Target	Proto-Oncogene Serine/threonine-Protein Kinase Mos (Mos)
Clonality	Polyclonal
Reactivity	Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 301-329 amino acids from the C-terminal region of mouse Mos.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P00536 (UniProt, ExPASy)
UniProt Secondary AC	E9PV67, F6UHW1, Q61886, Q61887, Q78EH5
UniProt Entry Name	MOS_MOUSE
KEGG	mmu:17451
String	10090.ENSMUSP00000100789
Molecular Weight	Calculated MW: 37.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rat Mos.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Proto-Oncogene Serine/threonine-Protein Kinase Mos (Mos)

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