mouse p27Kip1 (pT197) Antibody

This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq].

Target	mouse p27Kip1 (pT197)
Clonality	Polyclonal
Target Modification	Thr197
Modification	Phosphorylation
Reactivity	Mouse
Tested Applications	ELISA, DB
Host	Rabbit
Recommended dilutions	DB: 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T197 of mouse p27Kip1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P46414 (UniProt, ExPASy)
UniProt Secondary AC	Q8BG74
UniProt Entry Name	CDN1B_MOUSE
KEGG	mmu:12576
String	10090.ENSMUSP00000003115
Molecular Weight	Calculated MW: 22.2 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on mouse p27Kip1 (pT197)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue