Mitochondrial Ubiquitin Ligase Activator of NFKB 1 (MUL1) Antibody

E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Target	Mitochondrial Ubiquitin Ligase Activator of NFKB 1 (MUL1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 272-301 amino acids from the C-terminal region of human MUL1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q969V5 (UniProt, ExPASy)
UniProt Secondary AC	B5M497, Q7Z431, Q9H9B5
UniProt Entry Name	MUL1_HUMAN
KEGG	hsa:79594
String	9606.ENSP00000264198
Molecular Weight	Calculated MW: 39.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Monkey MUL1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Mitochondrial Ubiquitin Ligase Activator of NFKB 1 (MUL1)

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