NEDD4-Like E3 Ubiquitin-Protein Ligase WWP1 (WWP1) Antibody

WWP1 Antibody is a Rabbit Polyclonal antibody against WWP1. WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined.

Target	NEDD4-Like E3 Ubiquitin-Protein Ligase WWP1 (WWP1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human WWP1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9H0M0 (UniProt, ExPASy)
UniProt Secondary AC	O00307, Q5YLC1, Q96BP4
UniProt Entry Name	WWP1_HUMAN
GeneID	11059
NCBI Accession	NP_008944.1
String	9606.ENSP00000427793
Molecular Weight	Calculated MW: 105 kDa Observed MW: 105 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on NEDD4-Like E3 Ubiquitin-Protein Ligase WWP1 (WWP1)

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