NF-Kappa-B Inhibitor Beta (NFKBIB) Antibody

Inhibits NF- kappa -B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF- kappa -B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.Tissue specificity: Expressed in all tissues examined.

Target	NF-Kappa-B Inhibitor Beta (NFKBIB)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human NFKBIB expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15653 (UniProt, ExPASy)
UniProt Secondary AC	A8K3F4, Q96BJ7
UniProt Entry Name	IKBB_HUMAN
Gene Symbol	NFKBIB
GeneID	4793
OMIM	604495
HGNC	7798
KEGG	hsa:4793
Ensembl	ENSG00000104825
String	9606.ENSP00000312988
Molecular Weight	45 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on NF-Kappa-B Inhibitor Beta (NFKBIB)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue