NKX2.5 Antibody

NKX2.5: NK2 transcription factor related, locus 5 (Drosophila), also known as CSX. It is a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

Target	NKX2.5
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA
Host	Mouse
Recommended dilutions	ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human NKX2.5 expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P52952 (UniProt, ExPASy)
UniProt Secondary AC	A8K3K0, B4DNB6, E9PBU6
UniProt Entry Name	NKX25_HUMAN
Gene Symbol	NKX2-5
GeneID	1482
OMIM	108900
HGNC	2488
KEGG	hsa:1482
Ensembl	ENSG00000183072
String	9606.ENSP00000327758
Molecular Weight	35 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on NKX2.5

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