Poly(A) Polymerase Gamma (PAPOLG) Antibody

This gene encodes a member of the poly (A) polymerase family which catalyzes template-independent extension of the 3' end of a DNA/RNA strand. This enzyme shares 60% identity to the well characterized poly (A) polymerase II (PAPII) at the amino acid level. These two enzymes have similar organization of structural and functional domains. This enzyme is exclusively localized in the nucleus and exhibits both nonspecific and CPSF (cleavage and polyadenylation specificity factor) /AAUAAA-dependent polyadenylation activity. This gene is located on chromosome 2 in contrast to the PAPII gene, which is located on chromosome 14.

Target	Poly(A) Polymerase Gamma (PAPOLG)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 685-714 amino acids from the C-terminal region of human PAPOLG.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9BWT3 (UniProt, ExPASy)
UniProt Secondary AC	B2RBH4, Q59G05, Q969N1, Q9H8L2, Q9HAD0
UniProt Entry Name	PAPOG_HUMAN
Gene Symbol	PAPOLG
String	9606.ENSP00000238714
Molecular Weight	Calculated MW: 82.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Poly(A) Polymerase Gamma (PAPOLG)

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