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Paired Box 3 (PAX3) Antibody
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Catalogue No: abx015953
Price:
US$420.50
(Size: 100 µl)
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This gene is a member of the paired box (PAX) family of transcription factors.Members of the PAX family typically contain a paired box domain and a paired-type homeodomain.These genes play critical roles during fetal development.Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma.The translocation t (2;13) (q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma.Alternative splicing results in transcripts encoding isoforms with different C-termini.
Research Articles on Paired Box 3 (PAX3)
| Target | Paired Box 3 (PAX3) |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human PAX3 (AA: 142-203) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| GeneID | 5077 |
| Molecular Weight | 53 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |