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Proliferating Cell Nuclear Antigen (PCNA) Antibody
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Catalogue No: abx031736
Price:
US$290.00
(Size: 80 µl)
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PCNA is found in the nucleus and is a cofactor of DNA polymerase delta. This protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway.
Research Articles on Proliferating Cell Nuclear Antigen (PCNA)
| Target | Proliferating Cell Nuclear Antigen (PCNA) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 89-117 amino acids from the Central region of human PCNA. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P12004 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R897, D3DW02 |
| UniProt Entry Name | PCNA_HUMAN |
| KEGG | hsa:5111 |
| String | 9606.ENSP00000368458 |
| Molecular Weight | Calculated MW: 28.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow, Chicken, Hamster and Monkey PCNA. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |