Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1B (PDE1B) Antibody

Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin (see MIM 114180) dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).

Target	Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1B (PDE1B)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 467-495 amino acids from the C-terminal region of human PDE1B.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q01064 (UniProt, ExPASy)
UniProt Secondary AC	Q92825, Q96KP3
Molecular Weight	Calculated MW: 61.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1B (PDE1B)

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