Peptidyl-tRNA Hydrolase ICT1, Mitochondrial (ICT1) Antibody

Peptidyl-tRNA Hydrolase ICT1, Mitochondrial (ICT1) Antibody is a Rabbit Polyclonal antibody for the detection of ICT1.

Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.This antibody is a rabbit polyclonal antibody raised against a full-length human ICT1 protein

Target	Peptidyl-tRNA Hydrolase ICT1, Mitochondrial (ICT1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/200 - 1/2000, IHC: 1/20 - 1/200, IF/ICC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	immature colon carcinoma transcript 1
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q14197 (UniProt, ExPASy)
UniProt Secondary AC	B2RAD1, Q53HM7, Q53Y11
UniProt Entry Name	ICT1_HUMAN
Gene Symbol	MRPL58
GeneID	3396
KEGG	hsa:3396
String	9606.ENSP00000301585
Molecular Weight	Observed MW: 21-24 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Peptidyl-tRNA Hydrolase ICT1, Mitochondrial (ICT1)

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