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Prohibitin-2 (PHB2) Antibody
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Catalogue No: abx033287
Price:
US$326.25
(Size: 80 µl)
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PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. It functions as an estrogen receptor (ER) selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity and is probably involved in regulating mitochondrial respiration activity and in aging.
Research Articles on Prohibitin-2 (PHB2)
| Target | Prohibitin-2 (PHB2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/250. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 225-255 amino acids from human PHB2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q99623 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DP75, Q2YDA4, Q7KYU3, Q92978 |
| UniProt Entry Name | PHB2_HUMAN |
| Gene Symbol | PHB2 |
| KEGG | hsa:11331 |
| String | 9606.ENSP00000441875 |
| Molecular Weight | Calculated MW: 33.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow PHB2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |