POU Class 5 Homeobox 1 / OCT4 (POU5F1) Antibody

This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t (6;22) (p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. This antibody is supplied as crude ascites.

Target	POU Class 5 Homeobox 1 / OCT4 (POU5F1)
Clonality	Monoclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Mouse
Recommended dilutions	WB: 1/500 - 1/4000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Human POU5F1 recombinant protein.
Isotype	IgM
Form	Liquid
Purification	Unpurified crude ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q01860 (UniProt, ExPASy)
UniProt Entry Name	PO5F1_HUMAN
KEGG	hsa:5460
String	9606.ENSP00000259915
Molecular Weight	Calculated MW: 38.6 kDa
Buffer	Ascites containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on POU Class 5 Homeobox 1 / OCT4 (POU5F1)

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